• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    ELECTROSURGICAL DEVICE, ELECTROSURGICAL INSTRUMENT FOR USE IN AN ELECTROSURGICAL DEVICE AND TREATMENT UNIT OF AN ELECTROSURGICAL DEVICE The present invention relates to an electrosurgical device, characterized in that it comprises an electrosurgical instrument, a detection device for the detection of a predetermined component of the atmosphere in region of a treatment room and a treatment unit with a current generator for providing high-frequency energy that can be connected to q instrument, the treatment unit being provided with means for influencing the treatment process as a function of a signal output of the detection device.
    公开号:BR112012018969B1
    申请号:R112012018969-7
    申请日:2010-12-15
    公开日:2022-02-15
    发明作者:Klaus Fischer；Alexander Neugebauer；Matthias Voigtlandder；Daniel Schaller；Mara Szyrach；Jorg Kronenthaler；Lars Blobel；Irina Sigle；Markus D. Enderle
    申请人:Erbe Elektromedizin Gmbh；
    IPC主号:
    专利说明:

    [001] The present invention relates to an electrosurgical arrangement, which comprises an electrosurgical instrument and a treatment unit connectable with it for providing the energy necessary for a surgical intervention, especially high frequency energy. Furthermore, it refers to an electrosurgical instrument as well as a treatment unit of such an arrangement. Henceforth, the term “treatment unit” in the general sense designates a conventional high-frequency generator; in this respect more exact references will be made later.
    [002] Surgical provisions of this nature are known and used for a long time in the clinical field and in isolation, also in the ambulatory field. A multitude of the applicant's patent publications focus on its improvement in different aspects. In the case of the use of provisions of this nature, emissions are generated, more specifically combustion gases, which are made up of a large number of different organic molecules. It is known to eliminate said combustion gases from the atmosphere on the treatment site through specific suction devices, to avoid interference in the surgeon's work due to a worsening of visibility conditions.
    [003] A reduction of carbonization originating from the development of flue gases is already carried out through APC technology, and argon-based cutting in electrosurgery is a first measure, to keep carbonization as low as possible.
    [004] An analysis of the flue gases before electrosurgical applications susceptible to explosion is performed because the probability of the formation of a mixture of gases capable of causing explosions is reduced to a lower probability. This is achieved by the fact that the patient to be endoscoped before the operation is not given any food and that a comprehensive bowel cleansing by means of lavage is performed before the colonoscopy is performed.
    [005] In addition, a flue gas analysis can be used to reduce the likelihood of a fire or a fire in the gut or transbronchial system. To avoid fires and fires in the transbronchial system in the case of using APC, the oxygen concentration must be less than 40%. A flue gas analysis is furthermore suitable for a reduction of tissue carbonization and carcinogenic components, which are formed on the tissue surface and can be found in the flue gas. Finally, the surgeon's visibility of the region to be operated on is improved, particularly in closed lumens.
    [006] The object of the present invention is to provide an improved arrangement of the aforementioned nature, which particularly enables a more targeted influence of the cutting or treatment process and simultaneously the suppression of damage conditioned by emissions in the surgeon's work.
    [007] This objective is achieved from a system aspect through an electrosurgical arrangement in accordance with the features of claim 1 and with regard to individual system components through an electrosurgical instrument in accordance with the features of claim 13 or a treatment unit with the characteristics of claim 15.
    [008] The present invention is based on the thought that the emissions that arise during an electrosurgical process have a characteristic composition for the conduction of the process. Furthermore the present invention encompasses the thought of utilizing this available information rather than - as practiced heretofore - eliminating information-bearing emissions from the unused treatment site. This happens through the provision of a detection device for the analysis of emissions (combustion gases). Finally, the present invention encompasses the thought of using the analysis result to control the surgical process and provide corresponding means in the treatment unit. The treatment unit can essentially be manually controlled taking into account the analysis result, preferably however a direct control via an output signal from the detection device.
    [009] Through the analysis of these combustion gases or aerosols, the following possibilities are generated: a. Carbonization is an unwanted side effect in almost all electrosurgical applications. Carbonization leads to reinforced tissue infection and an increase in post-operative problems. Therefore, a reduction in carbonization is required in electrosurgical applications (high frequency and APC applications). An implementation is possible through the determination of chemical substances relevant to the combustion of the flue gas and the re-coupling of the measurement signal for the control of the treatment unit. By introducing certain gaseous or liquid substances (oxidizing agents for the carbon to be generated) the size of the carbonization can be significantly reduced.b. In the case of electrosurgical applications under certain conditions there is a danger of a gas explosion, deflagration or fire. Through the analysis of the gaseous atmosphere in the place to be operated or the analysis of the flue gas in the case of electrosurgical applications, an explosion, a deflagration or a fire can be effectively avoided, considering that the high frequency energy is only released in the event of a non-explosive gas mixture. An example of this is preventing a colonic explosion by analyzing and evaluating the flammable methane and hydrogen gases in the colon. Another application possibility is provided by urology in relation to an application of APC with water, in which significant amounts of hydrogen are formed.c. Vaporization of biological tissue is a desired effect in the area of tumor removal and in other areas where biological tissue has to be removed without leaving a residue. Vaporization is established in the area of laser application. By means of a targeted, localized, as far as possible stoichiometric biological tissue burn, selective tissue vaporization is achieved even in electrosurgery. This vaporization should primarily be used for thinning tumor tissue.
    [010] For this purpose, the targeted and localized application of an oxidizing agent (eg oxygen) is necessary. d. Flue gases can be made up of a large number of different organic molecules, tumor markers, metabolites, DNA, membrane molecules, peptides, proteins and viruses. Through the analysis of the flue gas, the marker molecules can be analyzed, which allow, for example, the realization of a tissue differentiation. In this way healthy tissue can be differentiated from diseased tissue (eg tumorous) or a penetration effect can be detected by detecting certain substances in the mucous walls (stomach, esophagus, intestine). This results in increased safety against unwanted penetration damage and puncture.
    [011] The measurement principles of sensors can be chemical, electrochemical, spectroscopic, physical or physicochemical. Examples for this are the detection of measured values through fuel cells, for magnetism, electrochemical measuring cells, pellistors, piezoelectric components, electrical resistance, absorption of radiation, humidity, light, heat radiation, substantial characteristic of an environment , a distance, an expansion, a passage, a color, a magnetic field or a pH value.
    [012] Sensors with corresponding sensor driving can be integrated into a surgical instrument or be fixed externally to it and particularly through a semi-permeable membrane at the distal end of the surgical instrument to be protected before the penetration of harmful substances.
    [013] According to an embodiment of the present invention, it is provided that at least a part of the detection device is arranged in a distal region of the electrosurgical instrument. Alternatively, it may be provided that at least a part of the detection device is arranged in a region proximal to the electrosurgical instrument or at a distance from the instrument and the instrument has a first fluid channel for conducting gas to the detection device.
    [014] According to another preferred embodiment of the present invention, it is provided that the detection device has a flue gas detector, in particular an H2 or CH4 detector or a detector of tracer molecules. The actual embodiment of the detector may be based on the above-mentioned sensor principles, with commercially available compact and economical detectors being particularly preferred.
    [015] According to another embodiment of the present invention, it is provided that the detection device has means for cutting and an analysis device for analyzing the aerosol transported with the gas or particles of solid matter. Therefore, in the aforementioned sense, additional information can be provided for tissue differentiation and for tumor detection, which is not directly and necessarily used to control the ongoing surgical process. In this case, parts of the detection device can also be arranged in a place distant from the treatment room and the instrument in operation, for example in an analysis laboratory, and in this case they must be understood as a component of the electrosurgical arrangement.
    [016] According to another embodiment of the present invention, it is provided that the detection device has a sensor for detecting a physical quantity at the treatment site, in particular temperature or an optical quantity and/or a detector of distance for detecting a distance between the distal end of the electrosurgical instrument and a tissue to be treated. In this case, a connection with the above-mentioned sensor principles is also generated, namely by checking chemical bonds in the atmosphere of the treatment room. By way of example, an optical fiber conductor can be arranged in an additional channel, which makes it possible to analyze an optical measurement signal outside the endoscopic instrument, for example with the aid of UV-Vis spectroscopy.
    [017] According to another embodiment of the present invention, the means for influencing the treatment process have a source of fluids for providing a treatment fluid suitable for influencing the treatment process, particularly an oxygen cylinder or noble gas or a water tank for receiving water or an aqueous solution, and the electrosurgical instrument has a second fluid channel for conducting the treatment fluid to influence the treatment process at the instrument's distal end.
    [018] More particularly, the surgical instrument may additionally have one or more openings, which allow the extraction or lateral and/or frontal introduction of gaseous or liquid substances. Thus, for example, a suitable liquid or gaseous oxidizing agent, such as water or oxygen, can be introduced to reduce carbonization (see above), which leads to an improved post-operative curing process. Furthermore, the introduced substance can produce a cooling effect, which is reflected in the tissue effect. These openings can have different embodiments, for example circular, oval or semi-circular. The openings in the distal probe end can be designed so that an aerosol of a substance introduced in the liquid state is generated and can be applied to the biological tissue in the region of electrosurgical application.
    [019] In addition, it may be provided that the electrosurgical instrument or in fluid connection with it is provided with a first transport device for transporting gas in the distal-proximal direction and/or a second transport device for transporting a fluid from treatment for the influence of the treatment process in the proximal-distal direction. Said second transport device is particularly used for introducing a non-provided treatment fluid into a pressure vessel, for example in the case of adding a saline solution from an associated tank.
    [020] Both in the case of using a treatment fluid under pressure and in the case of a transport device for the treatment fluid, preferably means of control of passage are provided for controlling the amount of treatment fluid suitable for the influence of the treatment process introduced per unit of time. These passage control means act in the direction of the aforementioned means for influencing the treatment process, either individually or together with means for controlling the introduction of treatment energy, namely high frequency energy. As means of said nature, the arrangement preferably comprises a current generator control device signalically connected with the output of the detection device, particularly an on/off control and/or a power control.
    [021] The aforementioned second fluid channel according to another embodiment of the present invention is arranged within an electrosurgical electrode of the instrument. By means of an introduction of this nature, for example, an introduction of oxygen or the introduction of a mixture of oxygen with other gaseous substances with a suitable flow can be carried out, which leads to a vaporization of biological tissue. The sensor can detect the concentration of molecules relevant to combustion, and by regulating the generator power and/or the gas flow, tissue vaporization is maximized and carbonization is minimized. Therefore, tumor ablation using the APC or high frequency technique would be conceivable.
    [022] The characteristics attributed to the instrument in the aforementioned embodiments, particularly the first and/or the second fluid channel and/or an integrated detection device, simultaneously characterize the electrosurgical instrument as a relatively independent unit or product, as well as the characteristics attributed to the treatment unit characterize said unit as an independent unit.
    [023] The other advantages and utilities of the present invention are evidenced in the following description of preferred embodiments based on the figures. Where: Fig. 1 shows a schematic overview of an electrosurgical arrangement in accordance with the present invention; Fig. 2A - 2D show detailed views of exemplary embodiments of an electrosurgical instrument as a component of such an arrangement, respectively in a longitudinal sectional representation of the distal end and in a top view of the distal end; Fig. 3A and 3B show detailed views of other embodiments of the electrosurgical instrument, respectively as a longitudinal sectional representation of the distal end in a situation of application at a treatment site; Fig. 4A - 4D show detailed views of other embodiments of the electrosurgical instrument, respectively as a longitudinal sectional representation of the distal end in a situation of application at a treatment site; Fig. 5A and 5B respectively show a top view as well as a detail view (longitudinal section of the distal end) according to other embodiments of the electrosurgical instrument; Fig. 6 shows a functional block diagram according to an embodiment of the electrosurgical arrangement; Fig. 7A - 7C show pulse diagrams for evidence of embodiments of the mode of operation of a treatment unit according to the present invention, and; Fig. 8A and 8B show representations of exemplary evaluation devices of an electrosurgical arrangement in accordance with the present invention.
    [024] Fig. 1 schematically shows an electrosurgical arrangement 1 in operation in a biological tissue treatment site S T, whereby through the application of a treatment energy E an introduction of heat H is generated into the tissue and from the treatment site S into the atmosphere located above A, emissions are emitted, particularly flue gases G. The emissions are detected by means of a detection device 3, and the respective output signal is transmitted to a treatment unit 5, which in turn is on the output side. connected with an electrosurgical instrument 7, through which the treatment process is carried out in the treatment unit in a controlled manner and, in particular, the treatment energy E is emitted.
    [025] Fig. 2A shows in detail the distal end of an instrument 710 in operation at a treatment location S. In an instrument body 711 two lumens 712, 713 are provided, and in the smaller lumen 713, through which the combustion gases G of the atmosphere A above the treatment location, a flue gas detector 310 is arranged. A noble gas, for example argon, is added through the larger lumen 712 for washing a centrally arranged high-frequency electrode 714 to influence the process. of treatment at the treatment site S.
    [026] Figs. 2B - 2D show variants of the construction of the instrument shown in Fig. 2A, the functionally corresponding parts being denoted with references similar to those in Fig. 2A and thereafter are not explained again.
    [027] The design of the instrument 720 according to Fig. 2B differs from that of the instrument 710 due to a central arrangement of the larger lumen 722 for the introduction of noble gas, the high frequency electrode 724 in turn being concentrically arranged in the lumen 722. Uniformly distributed around the lumen 722 are arranged four smaller lumens 723a - 723d. Of these, the two lumens 723c and 723d serve for the extraction of gases G from the treatment region and for their detection by means of a gas detector 320, while the two outer lumens 723a and 723b introduce other fluids F (gases or liquids, in addition to of noble gas introduced through the central lumen) to the treatment site. As evidenced by the left part of the figure, the distal outlets of the outer lumens are not located on the front side of the instrument, but in the respective coating area. Thus, it is equally evident that the right part of this figure is not a top view of the instrument's distal end, but a cross-sectional representation near the distal end.
    [028] Fig. 2C shows as another variant an instrument 730, which is distinguished from the aforementioned instruments 710 and 720 by a staggered distal end with a raised central area 730a. Furthermore, in this case, several smaller lumens 733 with a circular cross-section are provided, as well as a larger lumen 735, which partially surrounds the central area 730a of the instrument in a C-shape, on which different detectors 331 and 332 are arranged for detection. of different components of G gases and/or other parameters of the atmosphere above the treatment site. The C735-shaped lumen in this case is arranged distally through a semipermeable membrane 736 to protect the detector arranged therein 332 against vapor or moisture released at the treatment site.
    [029] Fig. 2D as another variant shows an instrument 740, which like the aforementioned embodiments has a large lumen 742 for the introduction of high frequency energy as well as treatment fluids. Furthermore, only one additional individual lumen 743 is designed in the instrument body 741, which in this case has a sickle shape and therefore - as in the first embodiment according to Fig. 2A - an individual detector is provided for the analysis of G gases.
    [030] An essential modification in relation to the instrument 710 is that the high frequency electrode 744 in this case is designed as a metallic tube, through which a treatment fluid, particularly gaseous oxygen or a NaCl solution, can be conducted to the treatment site. In addition, the electrode 744 in this case is designed distally, protruding from the end of the instrument and has a thermally chargeable coating 744a of an electrical insulator on the respective end, to avoid (additional) carbonization due to intense electrical arcs in the event of an application APC Ceramic materials or also synthetic materials resistant to high temperatures, such as those based on PTFE, are considered as materials for coating 744a. A valve 744c on the front side of the electrode tube 744 produces a spray of a liquid introduced above the treatment site.
    [031] Fig. 3A as another embodiment shows an instrument 750 operating in a treatment location S, which in turn has several lumens 725, 753 and 755. Regarding the design and function of the lumens 752, 753 and the high frequency electrodes 754 arranged at lumen 752 the instrument corresponds to that shown in Fig. 2A and the above-mentioned instrument 710. In addition to the lumen 755 and the respective distal opening 755a obliquely arranged and enlarged towards the outside, it has a device for the introduction and for the directed and optionally sprayed output of a treatment fluid, such as for example a physiologically effective aqueous solution and/or an oxidizing agent. The slope and design of opening 755a is dimensioned such that treatment fluid under adequate pressure is drawn in a focused manner above the treatment site S.
    [032] Fig. 3B, as a modification of the instrument 740 shown in Fig. 2D and described above, shows a schematic representation of a multi-lumen water jet applicator 760 with a built-in active high frequency electrode 764, which is designed as a metallic tube, through which fluid is extracted with a high flow rate through it. of a valve opening 764a, to achieve the desired effect on tissue. The fluid introduced and the blood during the application of the probe on the tissue are drawn into the suction channel 762. Through another channel 763 substances, for example aerosols, are extracted in parallel with the application and analyzed under pressure from the instrument by a sensor. 360, which is attached to the distal end of the instrument.
    [033] Fig. 4A shows a schematic representation of a monopolar high-frequency instrument 770 for cutting biological tissue, in that the active electrode 774 is surrounded by a tube 761, through which the generated flue gas G can be extracted. In the tube, which can be arranged centrally or parallel to the axis of the active electrode, at the distal end is a sensor 370 for the analysis of flue gases.
    [034] Fig. 4B shows a schematic representation of another high-frequency monopolar instrument 780 for cutting biological tissue, in which the active electrode 784 at its tip has small openings 784a through which liquid or gaseous substances can escape, and which is designed, so that through an extraction tube 782, combustion gases G or aerosols can be extracted and analyzed through a sensor 380.
    [035] Fig. 4C shows the use of a slightly modified instrument 710' with respect to the embodiment according to Fig. 2A. This differs from the instrument 710 due to the hollow embodiment of the electrode 714', into which a treatment fluid is introduced to the treatment site S, and furthermore due to the distal mounting of a conically widening crown 717, which separates the atmosphere A above the treatment site S of the rest of the atmosphere. This crown 717 therefore more reliably prevents the outflow of combustion gases into the operating room and also enables efficient use of the introduced treatment fluids.
    [036] Fig. 4D shows in sketch form the use of an instrument 710'' at a treatment site S' in a hollow organ (eg, the intestine) of a patient. The particular constructive embodiment of this instrument 710'' consists of a distally placed cap 718 with two lateral openings 718a, 718b, through which combustion gases can be extracted into the instrument or treatment fluids can be led from the instrument for the treatment site S'. For the rest, the design corresponds to that of the above-mentioned instrument 710' or of the above-mentioned instrument 710 and is therefore not described again.
    [037] Fig. 5 shows an APC 790 instrument, which instrument body in turn is designed similarly to that of the instruments described above, so that references to individual parts or areas are based on Figs. 2A - 3B. The greatest similarity that the instrument 790 presents is with the instrument 710 according to Fig. 2A; an essential difference from this consists in the provision of a separate measurement probe 790a, which is displaceable in the lumen 793 in the proximal-distal direction and therefore can lead the detector 390 mounted thereon to particularly close to the treatment site.
    [038] Fig. 5B as a variant of this last mentioned embodiment shows another APC instrument 790', in which a displaceable measuring probe 790a together with the detector 390 is arranged in a modified (one lumen) instrument body 791' displaceably. Fixing brackets 796 are provided for fixing the probe 790a' to the base body 791' of the instrument, on which the probe can slide.
    [039] Fig. 6 schematically shows, in the form of a functional block diagram, an electrosurgical arrangement 1' with a surgical instrument 7', whose basic construction and use correspond to those of the arrangement shown in Fig. 1 and which is applied to a patient P. An emissions sensor 3' with an associated measurement amplifier performs a predetermined detection procedure at the treatment site, namely a flue gas analysis, a CO detection, a temperature detection or also a detection of the distance between the end of the instrument and the tissue etc., and the respective output signal, with the aim of an adequate influence of the treatment process, is introduced in different control devices. In this case, it is a question of a passage control 5a' for the gas flow of a treatment gas introduced from a gas cylinder, of a high frequency control device 5b' for controlling the treatment energy provided by a high frequency generator 4 and a cleaning fluid control 5c' to control the passage of a cleaning fluid provided from a source 6. Furthermore, the figure shows a schematic representation of the fact that in all "channels" for the influence of the treatment process, additional amplification devices or control devices 8a', 8b' and 8c' may be provided.
    [040] Figs. 7A - 7C exemplify in the form of pulse diagrams possibilities of modulating the flow of treatment gas through the first control device 5a' (Fig. 7A), of the power of the high frequency generator through the second control device 5b' (Fig. 7B) and the provision of cleaning fluid through the third control device 5c' (Fig. 7C).
    [041] Fig. 8A shows a principle sketch of a sensor system 30, in which the light emission at the treatment site S (at the visible or ultraviolet wavelength) is coupled to an optical fiber 31. This polychromatic light emission is filtered with the aid of of an optical filter 32, so that only one wavelength or a narrow band of wavelengths is admitted, which is characteristic of the process to be observed (for example, the process of carbonization of the fabric surface). This wavelength or this wavelength band is detected by a suitable photodiode 33 and transformed into a voltage signal, the voltage signal being proportional to the intensity of the wavelength or band of wavelengths filtered. This voltage signal is evaluated by an evaluation unit 34 and used for the control/regulation of the high frequency generator and the introduction of additives.
    [042] Fig. 8B shows a principle outline of another sensor system 30', in which the generated flue gas is used in an electrosurgical application by means of a pump 35 through a pipe (not shown) in the sensor box 30a. In the sensor box are a polychromatic light source and a monochromatic light source 36, an optical filter 32' and a photodiode 33. The optical filter filters an optical wavelength or a band of wavelengths from the polychromatic spectrum of the light source. (In the case of using a monochromatic light source it can be deleted). The radiation that leaves the filter falls on flue gas molecules G and is totally or partially absorbed by them. The residual radiation intensity falls on the photodiode, which, depending on the radiation intensity, generates a voltage signal. This voltage signal is evaluated by an evaluation unit 34' and used for the control/regulation of the high frequency generator and the introduction of additives.
    [043] The implementation of the present invention is not limited to the examples and aspects mentioned above, being also possible in a multitude of variants, which are within the scope of the skill.
    权利要求:
    Claims (9)
    [0001]
    1. ELECTROSURGICAL ARRANGEMENT (1), with an electrosurgical instrument (7, 710, 740, 750) for plasma coagulation, a detection device (3) for the detection of a predetermined constituent of the atmosphere in the region of a treatment site (S ), whose device features a sensor for detecting an optical variable at the treatment site and a distance sensor for detecting a distance between the distal end of the electrosurgical instrument and a tissue (T) to be treated, and a treatment unit ( 5), which can be connected to the instrument (7) and has a current generator (4) for providing high frequency (RF) energy, characterized by the means to influence the treatment process as a function of the sensor output signals and distance sensor of the sensing device are provided in the treatment unit, wherein the means for influencing the treatment process has a control device of the power generator which is connected to the output of the device. positive detection in terms of signaling, and also have a fluid source to supply a suitable treatment fluid to influence the treatment process, where the fluid source is a noble gas cylinder and where the control device is configured to control the treatment energy (E) provided by the power generator and wherein the instrument has a first fluid channel for conducting the treatment fluid through the distal end of the instrument.
    [0002]
    2. ELECTROSURGICAL ARRANGEMENT, according to claim 1, characterized in that at least a part of the detection device is arranged in a distal region of the electrosurgical instrument.
    [0003]
    3. ELECTROSURGICAL ARRANGEMENT, according to claim 1, characterized in that at least a part of the detection device is arranged in the proximal region of the instrument or at a distance from the instrument and the instrument has a second fluid channel for the conduction of gas to the device. of detection.
    [0004]
    4. ELECTROSURGICAL ARRANGEMENT, according to any one of claims 1 to 3, characterized in that the detection device has means for deposition and an analysis device for the analysis of aerosol or solid particles carried with the solid matter gas.
    [0005]
    5. ELECTROSURGICAL ARRANGEMENT according to any one of claims 1 to 4, characterized by a first transport device for transporting a treatment fluid in the distal-proximal direction and/or a second transport device for transporting gas from treatment for the influence of the treatment process in the proximal-distal direction to be provided on or in fluid connection with the instrument.
    [0006]
    6. ELECTROSURGICAL ARRANGEMENT, according to claim 5, characterized in that it comprises control means for controlling the amount of treatment fluid that is supplied to the treatment site per unit of time.
    [0007]
    7. ELECTROSURGICAL ARRANGEMENT according to any one of claims 1 to 6, characterized in that the instrument at or near the distal end has a plurality of openings connected with the first fluid channel for the spatially distributed outlet of the treatment fluid.
    [0008]
    8. ELECTROSURGICAL ARRANGEMENT, according to any one of claims 1 to 7, characterized in that the first fluid channel is arranged inside an electrosurgical electrode (714) of the instrument.
    [0009]
    9. ELECTROSURGICAL DEVICE, according to any one of claims 1 to 8, characterized in that the power generator control device is configured for activation/deactivation control and/or a high frequency power output control.
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    法律状态:
    2019-01-08| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-08-06| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-09-08| B06A| Patent application procedure suspended [chapter 6.1 patent gazette]|
    2022-01-11| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2022-02-15| B16A| Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/12/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |
    优先权:
    申请号 | 申请日 | 专利标题
    DE102010000305.0|2010-02-04|
    DE102010000305|2010-02-04|
    DE102010015899A|DE102010015899A1|2010-02-04|2010-03-10|Electrosurgical device and electrosurgical instrument|
    DE102010015899.2|2010-03-10|
    PCT/EP2010/069755|WO2011095253A1|2010-02-04|2010-12-15|Electrosurgical assembly and electrosurgical instrument|
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